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李鹏松 副教授
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E- mail: pengsongli@bjfu.edu.cn
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研究方向:环境与能源微生物
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个人履历
教育经历:
2005.09-2009.07---北京大学,生命科学学院,生物技术专业,学士
2009.09-2015.07---北京大学,十大正规赌网站,环境科学专业,博士
2013.09-2014.09---美国斯坦福大学/橡树岭国家实验室,国家公派访问博士
主要工作经历:
2015.07-2019.07---清华大学,核能与新能源技术研究院,博士后/助理研究员
2019.07-2020.12---公司,十大正规赌网站,讲师
2021.01至今-------公司,十大正规赌网站,副教授
本科生课程:
《水处理微生物学》《水处理微生物学实验》《认识实习》《毕业实习》
研究生课程:
《环境微生物图谱解析》《实验样品生物分析技术》
主要研究领域:
1. 微生物对环境胁迫的响应机制
2. 抗胁迫微生物的筛选、构建与应用
3. 二氧化碳的微生物转化
4. 环境中生物多样性研究
代表性研究项目:
01. 国家重点研发计划“长江黄河等重点流域水资源与水环境综合治理”重点专项课题,2021YFC3200602,基于碳源高效回收的污水生物-生态耦合处理新技术研究(所属项目:污水生物处理前沿技术研发与示范),2021.12-2025.11(参加)
02. 国家自然科学基金面上项目,52070016,解磷菌耦合异化铁还原诱导次生成矿对沉积物镉的固定作用及机制研究,2021.01-2024.12(参加)
03. 中央高校基本科研业务费专项资金项目,BLX201934,硫还原地杆菌cad操纵子的鉴定与镉生物传感器构建研究,2020.01-2021.12(主持)
04. 中国博士后科学基金特别资助项目,2017T100064,基于CRISPR的耐乙醇马克斯克鲁维酵母构建及机理研究,2017.07-2019.06(主持)
05. 国家自然科学基金青年基金项目,31600067,CRISPR/Cas9介导的基因组进化构建固态发酵耐热酵母及机理研究,2017.01-2018.12(主持)
06. 国家重点研发计划“政府间国际科技创新合作”重点专项,2016YFE0108500,利用基因组全局进化工程构建耐热燃料乙醇固体发酵酵母,2016.12-2019.11(参加)
07. 中国博士后科学基金面上资助项目,2015M581074,生物乙醇生产过程中耐热酵母的分子育种研究,2015.12-2017.06(主持)
08. 深圳市基础研究项目,JCYJ20130329174424934,高效吸附重金属镉的工程酵母菌构建及其应用基础研究,2013.07-2015.07(参加)
09. 深港创新圈项目,JSE201109160056A,纤维素类生物质厌氧生物制氢的关键技术及应用研究,2013.01-2014.12(参加)
代表性文章
01. Pengsong Li, Qian Chen, He Dong, Jialin Lu, Dezhi Sun, Yue Wei, Hao He, Ruting Tang, Yumeng Li, Yan Dang*, Effect of applying potentials on anaerobic digestion of high salinity organic wastewater. Science of the Total Environment, 2022, 822: 153416.
02. Pengsong Li*, Xianwei Tan, Xiaofen Fu, Yan Dang, Shizhong Li*, Metabolomic analysis reveals Kluyveromyces marxianus’s stress responses during high-temperature ethanol fermentation, Process Biochemistry, 2021, 102: 386-392.
03. Pengsong Li, Yumingzi Wang, Xin Yuan, Xinying Liu, Chunmao Liu, Xiaofen Fu, Dezhi Sun, Yan Dang*, Dawn E. Holmes, Development of a whole-cell biosensor based on an ArsR-Pars regulatory circuit from Geobacter sulfurreducens. Environmental Science and Ecotechnology, 2021, 6: 100092.
04. Pengsong Li*, Xiaofen Fu, Lei Zhang, Shizhong Li*, CRISPR/Cas-based screening of a gene activation library in Saccharomyces cerevisiae identifies a crucial role of OLE1 in thermotolerance, Microbial Biotechnology, 2019, 12 (6), 1154-1163
05. Pengsong Li, Xiaofen Fu, Ming Chen, Lei Zhang, Shizhong Li*, Proteomic profiling and integrated analysis with transcriptomic data bring new insights in the stress responses of Kluyveromyces marxianus after an arrest during high-temperature ethanol fermentation, Biotechnology for Biofuels, 2019, 12: 49
06. Peng-Song Li, Wei-Min Wu*, Debra H. Phillips, David B. Watson, Shelly Kelly, Bing Li, Tonia Mehlhorn, Kenneth Lowe, Jennifer Earles, Hu-Chun Tao, Tong Zhang, Craig S. Criddle*, Uranium sequestration in sediment at an iron-rich contaminated site at Oak Ridge, Tennessee via. bioreduction followed by reoxidation, Journal of Environmental Sciences, 2019, 85: 156-167
07. Xiaofen Fu, Pengsong Li*, Lei Zhang, Shizhong Li*, Understanding the stress responses of Kluyveromyces marxianus after an arrest during high-temperature ethanol fermentation based on integration of RNA-Seq and metabolite data, Applied Microbiology and Biotechnology, 2019, 103: 2715-2729
08. Pengsong Li*, Xiaofen Fu, Shizhong Li*, Lei Zhang, Engineering TATA-binding protein Spt15 to improve ethanol tolerance and production in Kluyveromyces marxianus, Biotechnology for Biofuels, 2018, 11: 207
09. Xiaofen Fu, Pengsong Li*, Lei Zhang, Shizhong Li*, RNA-Seq-based transcriptomic analysis of Saccharomyces cerevisiae during solid-state fermentation of crushed sweet sorghum stalks, Process Biochemistry, 2018, 68: 53-63
10. Pengsong Li, Xiaofen Fu, Lei Zhang, Zhiyu Zhang, Jihong Li, Shizhong Li*, The transcription factors Hsf1 and Msn2 of thermotolerant Kluyveromyces marxianus promote cell growth and ethanol fermentation of Saccharomyces cerevisiae at high temperatures, Biotechnology for Biofuels, 2017, 10: 289
11. Hu-Chun Tao*, Peng-Song Li, Qi-Song Liu, Jie Su, Guo-Yu Qiu, Zi-Gang Li*, Surface-engineered Saccharomyces cerevisiae cells displaying redesigned CadR for enhancement of adsorption of cadmium (II), Journal of Chemical Technology and Biotechnology, 2016, 91: 1889-1895
12. Peng-Song Li, Hu-Chun Tao*, Cell surface engineering of microorganisms towards adsorption of heavy metals, Critical Reviews in Microbiology, 2015, 41(2): 140-149
13. Peng-Song Li, Zhi-Wen Peng, Jie Su, Hu-Chun Tao*, Construction and optimization of a Pseudomonas putida whole-cell bioreporter for detection of bioavailable copper, Biotechnology Letters, 2014, 36(4): 761-766
发明专利
01. 李十中,李鹏松,付晓芬,一种促进马克斯克鲁维酵母目的基因的表达的载体,中国,ZL201910014720.6,授权日:2020.12.25.
02. 李鹏松,陶虎春,苏捷,于太安,彭智文,一种表面展示重组蛋白的工程酿酒酵母活细胞镉吸附剂,中国,ZL201210160042.2,授权日:2015.6.17
03. 李鹏松,陶虎春,彭智文,苏捷,于太安,一种利用细菌全细胞生物传感器检测铜浓度的方法,中国,ZL201210309671.7,授权日:2015.5.13
01. 国家自然科学基金项目评议专家
02. Biotechnology for Biofuels、Applied Microbiology and Biotechnology等期刊审稿人
01. 2020-2021学年公司优秀班主任
02. 2021年第十四届全国大员工节能减排社会实践与科技竞赛三等奖指导教师
03. 2021年第三届北京市大员工节能节水低碳减排社会实践与科技竞赛二等奖、三等奖指导教师
04. 2021年公司大员工节能减排社会实践与科技竞赛一等奖、三等奖指导教师
05. 2020年第二届北京市大员工节能节水低碳减排社会实践与科技竞赛一等奖指导教师