个人履历

教育经历：

2005.9-2009.7---北京大学，生物技术专业，获学士学位

2009.9-2015.7---北京大学，环境科学专业，获博士学位

主要工作经历：

2013.9-2014.9---美国橡树岭国家实验室，环境科学部，访问学者

2013.9-2014.9---美国斯坦福大学，土木与环境工程系，访问学者

2015.7-2019.7---清华大学，核能与新能源技术研究院，博士后/助理研究员

2019.7-至今-----公司，十大正规赌网站，讲师

教学工作

本科生课程：

《环境微生物学实验》

研究生课程：

《环境微生物图谱解析》

科学研究

主要研究领域：

1. 重金属离子的生物检测与生物吸附

2. 抗逆微生物菌株构建与多组学分析

代表性研究项目：

01. 国家自然科学基金青年基金项目，CRISPR/Cas9介导的基因组进化构建固态发酵耐热酵母及机理研究，2017.01-2018.12，17万元（主持）

02. 中国博士后科学基金“特别资助”项目，基于CRISPR的耐乙醇马克斯克鲁维酵母构建及机理研究，2017.07-2019.06，15万元（主持）

03. 中国博士后科学基金“面上资助”项目，生物乙醇生产过程中耐热酵母的分子育种研究，2015.12-2017.06，5万元（主持）

04. 国家重点研发计划“政府间国际科技创新合作”重点专项，利用基因组全局进化工程构建耐热燃料乙醇固体发酵酵母，2016.12-2019.11，440万元（技术骨干，排名：3/13）

05. 美国斯坦福大学与橡树岭国家实验室合作的美国能源部地下生物地球化学研究计划(U.S. DOE Subsurface Biogeochemical Research Program), Long-Term Sequestration of Uranium in Iron-Rich Sediment, 2012.01-2014.12（技术骨干）

06. 深圳市基础研究项目，高效吸附重金属镉的工程酵母菌构建及其应用基础研究，2013.07-2015.07（技术骨干）

07. 深港创新圈项目，纤维素类生物质厌氧生物制氢的关键技术及应用研究，2013.01-2014.12（技术骨干）

代表性文章

01. Pengsong Li, Xiaofen Fu, Ming Chen, Lei Zhang, Shizhong Li*, Proteomic profiling and integrated analysis with transcriptomic data bring new insights in the stress responses of Kluyveromyces marxianus after an arrest during high-temperature ethanol fermentation, Biotechnology for Biofuels, 2019, 12: 49

02. Peng-Song Li, Wei-Min Wu*, Debra H. Phillips, David B. Watson, Shelly Kelly, Bing Li, Tonia Mehlhorn, Kenneth Lowe, Jennifer Earles, Hu-Chun Tao, Tong Zhang, Craig S. Criddle*, Uranium sequestration in sediment at an iron-rich contaminated site at Oak Ridge, Tennessee via. bioreduction followed by reoxidation, Journal of Environmental Sciences, 2019, 85: 156-167

03. Xiaofen Fu#, Pengsong Li#,*, Lei Zhang, Shizhong Li*, Understanding the stress responses of Kluyveromyces marxianus after an arrest during high-temperature ethanol fermentation based on integration of RNA-Seq and metabolite data, Applied Microbiology and Biotechnology, 2019, 103: 2715-2729

04. Ming Chen, Yanxue Li, Pengsong Li, Wenrui Wang, Lisong Qi, Peipei Li, Shizhong Li*, A novel native bioenergy green alga can stably grow on waste molasses under variable temperature conditions, Energy Conversion and Management, 2019, 196: 751-758

05. Pengsong Li#,*, Xiaofen Fu#, Shizhong Li*, Lei Zhang, Engineering TATA-binding protein Spt15 to improve ethanol tolerance and production in Kluyveromyces marxianus, Biotechnology for Biofuels, 2018, 11: 207

06. Pengsong Li*, Xiaofen Fu, Lei Zhang, Shizhong Li*, CRISPR/Cas-based screening of a gene activation library in Saccharomyces cerevisiae identifies a crucial role of OLE1 in thermotolerance, Microbial Biotechnology, 2018, DOI: 10.1111/1751-7915.13333

07. Xiaofen Fu#, Pengsong Li#,*, Lei Zhang, Shizhong Li*, RNA-Seq-based transcriptomic analysis of Saccharomyces cerevisiae during solid-state fermentation of crushed sweet sorghum stalks, Process Biochemistry, 2018, 68: 53-63

08. Bing Li, Wei-Min Wu*, David B. Watson, Erick Cardenas, Yuanqing Chao, D. H. Phillips, Tonia Mehlhorn, Kenneth Lowe, Shelly D. Kelly, Pengsong Li, Huchun Tao, James M. Tiedje, Craig S. Criddle, Tong Zhang*, Bacterial community shift and coexisting/coexcluding patterns revealed by network analysis in a uranium-contaminated site after bioreduction followed by reoxidation, Applied and Environmental Microbiology, 2018, 84(9): e02885-17

09. Pengsong Li#, Xiaofen Fu#, Lei Zhang, Zhiyu Zhang, Jihong Li, Shizhong Li*, The transcription factors Hsf1 and Msn2 of thermotolerant Kluyveromyces marxianus promote cell growth and ethanol fermentation of Saccharomyces cerevisiae at high temperatures, Biotechnology for Biofuels, 2017, 10: 289

10. Hu-Chun Tao*, Peng-Song Li, Qi-Song Liu, Jie Su, Guo-Yu Qiu, Zi-Gang Li*, Surface-engineered Saccharomyces cerevisiae cells displaying redesigned CadR for enhancement of adsorption of cadmium (II), Journal of Chemical Technology and Biotechnology, 2016, 91: 1889-1895

11. Hu-Chun Tao*, Jie Su, Peng-Song Li, He-Ran Zhang, Guo-Yu Qiu, Specific adsorption of silver (I) from aqueous phase by Saccharomyces cerevisiae cells with enhanced displaying CueR protein, Journal of Environmental Engineering, 2016, 142(9): C4015018

12. Peng-Song Li, Hu-Chun Tao*, Cell surface engineering of microorganisms towards adsorption of heavy metals, Critical Reviews in Microbiology, 2015, 41(2): 140-149

13. Peng-Song Li, Zhi-Wen Peng, Jie Su, Hu-Chun Tao*, Construction and optimization of a Pseudomonas putida whole-cell bioreporter for detection of bioavailable copper, Biotechnology Letters, 2014, 36(4): 761-766

14. Hu-Chun Tao*, Zhi-Wen Peng, Peng-Song Li, Tai-An Yu, Jie Su, Optimizing cadmium and mercury specificity of CadR-based E. coli biosensors by redesign of CadR, Biotechnology Letters, 2013, 35(8): 1253-1258

发明专利

01. 李鹏松，陶虎春，苏捷，于太安，彭智文，一种表面展示重组蛋白的工程酿酒酵母活细胞镉吸附剂，中国，ZL201210160042.2，已授权，授权日：2015.6.17

02. 李鹏松，陶虎春，彭智文，苏捷，于太安，一种利用细菌全细胞生物传感器检测铜浓度的方法，中国，ZL201210309671.7，已授权，授权日：2015.5.13

03. 李十中，李鹏松，仉磊，付晓芬，一种马克思克鲁维酵母质粒载体及其应用，中国，201610944729.3，实审，申请日：2016.11.2

04. 李十中，李鹏松，付晓芬，一种促进马克斯克鲁维酵母目的基因的表达的载体，中国，201910014720.6，实审，申请日：2019.1.8

05. 李十中，李鹏松，付晓芬，一种抑制马克斯克鲁维酵母目的基因的表达的载体，中国，201910014726.3，实审，申请日：2019.1.8

社会工作

荣誉